5.7. Upgrading a Replication Setup
5.7.1. Upgrading Replication to 5.0
This section applies to upgrading replication from MySQL 3.23, 4.0, or 4.1 to MySQL 5.0. A 4.0 server should be 4.0.3 or newer.
When you upgrade a master to 5.0 from an earlier MySQL release series, you should first ensure that all the slaves of this master are using the same 5.0.x release. If this is not the case, you should first upgrade the slaves. To upgrade each slave, shut it down, upgrade it to the appropriate 5.0.x version, restart it, and restart replication. The 5.0 slave is able to read the old relay logs written prior to the upgrade and to execute the statements they contain. Relay logs created by the slave after the upgrade are in 5.0 format.
After the slaves have been upgraded, shut down the master, upgrade it to the same 5.0.x release as the slaves, and restart it. The 5.0 master is able to read the old binary logs written prior to the upgrade and to send them to the 5.0 slaves. The slaves recognize the old format and handle it properly. Binary logs created by the master following the upgrade are in 5.0 format. These too are recognized by the 5.0 slaves.
In other words, there are no measures to take when upgrading to MySQL 5.0, except that the slaves must be MySQL 5.0 before you can upgrade the master to 5.0. Note that downgrading from 5.0 to older versions does not work so simply: You must ensure that any 5.0 binary logs or relay logs have been fully processed, so that you can remove them before proceeding with the downgrade.
Downgrading a replication setup to a previous version cannot be done once you've switched from statement-based to row-based replication, and after the first row-based statement has been written to the binlog. See Section 5.3, "Row-Based Replication."